Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
FLNA / Filamin A is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.
Gene Name: | filamin A, alpha |
Synonyms: | FLNA, ABPX, Actin binding protein 280, Actin-binding protein 280, Filamin A, FLN1, FMD, Filamin-A, Filamin-1, FLN, FLN-A, Non-muscle filamin, OPD1, OPD2, Alpha-filamin, NHBP, OPD, XMVD, CVD1, Filamin A, alpha, MNS, XLVD |
Target Sequences: | NM_001456 NP_001447.2 P21333 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.