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FIS1
fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis. Also mediates peroxisomal fission.
| Gene Name: | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) |
| Synonyms: | FIS1, CGI-135, FIS1 homolog, HFis1, TPR repeat protein 11, TTC11, H_NH0132A01.6 |
| Target Sequences: | NM_016068 NP_057152.2 Q9Y3D6 |
Publications (1)
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