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FHL3

four and a half LIM domains 3

The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene.

Gene Name: four and a half LIM domains 3
Synonyms: FHL3, FHL-3, Four and a half LIM domains 3, LIM-only protein FHL3, Skeletal muscle lim-protein 2, SLIM2, SLIM-2
Target Sequences: NM_004468 NP_004459.2 Q13643

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Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
FHL3 (7)
No (7)
GST (1)
GST, N-terminus (2)
His (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
E. coli (2)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (3)
FHL3 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
FHL3 Protein - Purified recombinant protein FHL3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
31 kDa
20 µg/$1,107
FHL3 Protein - 12.5% SDS-PAGE of human FHL3 stained with Coomassie Blue
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Wheat Germ Extract
GST
56.43 kDa
10 µg/$479; 25 µg/$670
FHL3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
31 kDa
20 µg/$150
FHL3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
31 kDa
100 µg/$494
FHL3 Protein
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E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
FHL3 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
GST, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Viewing 1-7 of 7 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).