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Fgf15

fibroblast growth factor 15

Fibroblast growth factor 15 is a protein in mouse encoded by the Fgf15 gene. It is a member of the fibroblast growth factor (FGF) family but, like FGF19, FGF21 and FGF23, has endocrine functions. FGF19 is the orthologous protein in humans. They are often referred together as FGF15/19.

Gene Name: fibroblast growth factor 15
Synonyms: Fgf15
Target Sequences: NP_032029.1 O35622

Publications (6)

1
Myeloid Cell-Specific Lipin-1 Deficiency Stimulates Endocrine Adiponectin-FGF15 Axis and Ameliorates Ethanol-Induced Liver Injury in Mice. Wang J, Kim C, Jogasuria A, Han Y, Hu X, Wu J, Shen H, Chrast R, Finck BN, You M. Scientific reports. 2016 September;6:34117. [Full Text Article] [PubMed:27666676] [PMC:PMC5036185]
2
Theabrownin from Pu-erh tea attenuates hypercholesterolemia via modulation of gut microbiota and bile acid metabolism. Huang F, Zheng X, Ma X, Jiang R, Zhou W, Zhou S, Zhang Y, Lei S, Wang S, Kuang J, Han X, Wei M, You Y, Li M, Li Y, Liang D, Liu J, Chen T, Yan C, Wei R, Rajani C, Shen C, Xie G, Bian Z, Li H, Zhao A, Jia W. Nature communications. 2019 October;10:4971. [Full Text Article] [PubMed:31672964] [PMC:PMC6823360]
3
Transgenerational impact of maternal obesogenic diet on offspring bile acid homeostasis and nonalcoholic fatty liver disease. Michael D Thompson, Alaina Derse, Jeremie LA Ferey, Michaela Reid, Yan Xie, Miranda Christ, Deyali Chatterjee, Chau Nguyen, Natalia Harasymowicz, Farshid Guilak, Kelle H Moley, Nicholas Oliver Davidson. American journal of physiology. Endocrinology and metabolism. 2019 April;316:E674-E686. [Full Text Article] [PubMed:30860882] [PMC:PMC6482665]
4
Monomeric/dimeric forms of Fgf15/FGF19 show differential activity in hepatocyte proliferation and metabolic function. Courtney M Williams, Jessica Harper Calderon, Hock E, Yasalp Jimenez, Kevin Barringer, Marisa Carbonaro, Maria Del Pilar Molina-Portela, Gavin Thurston, Zhe Li, Christopher Daly. The Breast : official journal of the European Society of Mastology. 2021 Feb;;35:e21286. [Full Text Article] [PubMed:33484478] Related Antibodies: LS-B15011.
5
Selective PPARd agonist seladelpar suppresses bile acid synthesis by reducing hepatocyte CYP7A1 via the fibroblast growth factor 21 signaling pathway. Tetsuya Kouno, Xiao Liu, Huayi Zhao, Tatiana Kisseleva, Edward E Cable, Bernd Schnabl. The Journal of biological chemistry. 2022 July;298:102056. [Full Text Article] [PubMed:35605662] [PMC:PMC9214809]
6
FGF15 promotes hepatic NPC1L1 degradation in lithogenic diet-fed mice. Pingfan Mo , Hongtan Chen , Xin Jiang, Fengling Hu, Fenming Zhang, Guodong Shan, Wenguo Chen, Sha Li, Yiqiao Li, Guoqiang Xu. Lipids in health and disease. 2022 October;21:97. [Full Text Article] [PubMed:36209166] [PMC:PMC9547418]
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Fgf15 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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1 mg/$1,679; 100 µg/$500; 20 µg/$364
Fgf15 Protein - Recombinant  Fibroblast Growth Factor 15 By SDS-PAGE
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10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).