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FGF13 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. This gene is located in a region on chromosome X, which is associated with Borjeson-Forssman-Lehmann syndrome (BFLS), making it a possible candidate gene for familial cases of the BFLS, and for other syndromal and nonspecific forms of X-linked mental retardation mapping to this region. Alternative splicing of this gene at the 5' end results in several transcript variants encoding different isoforms with different N-termini.
Gene Name: | fibroblast growth factor 13 |
Family/Subfamily: | HBGF , not assigned-HBGF |
Synonyms: | FGF13, FHF-2, FHF2, Fibroblast growth factor 13, FGF-13 |
Target Sequences: | NM_004114 NP_004105.1 Q92913 |
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