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FECH / Ferrochelatase

ferrochelatase

FECH / Ferrochelatase is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.

Gene Name: ferrochelatase
Synonyms: FECH, FCE, Heme synthase, EPP, Heme synthetase, Protoheme ferro-lyase, Protoporphyria, Ferrochelatase, Ferrochelatase, mitochondrial
Target Sequences: NM_000140 NP_000131.2 P22830

Publications (2)

1
Silencing of ferrochelatase enhances 5-aminolevulinic acid-based fluorescence and photodynamic therapy efficacy. Teng L, Nakada M, Zhao SG, Endo Y, Furuyama N, Nambu E, Pyko IV, Hayashi Y, Hamada JI. British journal of cancer. 2011 104:798-807. (WB; Human) [Full Text Article] [PubMed:21304523] Related Antibodies: LS-C307514.
2
Ferrochelatase regulates retinal neovascularization. Sardar Pasha Sheik Pran Babu, Darcy White, Timothy W Corson. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2020 September;34:12419-12435. [Full Text Article] [PubMed:32716567] [PMC:PMC7726024 (ava] Related Antibodies: LS-C409953.

☰ Filters
Antibodies (28)
ELISA Kits (9)
Proteins (9)
Custom (3)
Over-Expression Lysate (4)
Primary (28)
Recombinant (5)
Sandwich (6)
FECH / Ferrochelatase (46)
Human (31)
Mouse (10)
Rat (9)
Bat (3)
Bovine (3)
Chicken (1)
Chimpanzee (6)
Dog (3)
Gibbon (6)
Guinea pig (3)
Horse (3)
Monkey (9)
Orangutan (6)
Pig (3)
Rabbit (6)
Zebrafish (3)
IHC (9)
IHC-P (6)
WB (27)
ELISA (3)
IF (1)
Peptide-ELISA (1)
rabbit (26)
mouse (2)
IgG (14)
IgG2b,k (1)
monoclonal mc (1)
polyclonal pc (27)
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96-Well Strip Plate (9)
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APC Conjugated (1)
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PE Conjugated (1)
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aa55-423 (8)
aa100-149 (4)
aa252-301 (4)
aa51-100 (4)
No (44)
Yes (2)
Cell Culture Supernatants (1)
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GST (1)
GST, N-terminus (1)
His-T7 (1)
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Human (7)
293T Cells (2)
E. coli (1)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (1)
FECH / Ferrochelatase Antibody - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:100.
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FECH / Ferrochelatase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
20 µl/$275; 100 µl/$389
FECH / Ferrochelatase Protein - Recombinant  Ferrochelatase By SDS-PAGE
Select
E. coli
His-T7
45.9 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
FECH / Ferrochelatase Antibody - Western blot of FECH / Ferrochelatase antibody.
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FECH / Ferrochelatase Rabbit anti-Human Polyclonal (aa55-423) Antibody
Human
WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
FECH / Ferrochelatase Antibody - Western blot of FECH / Ferrochelatase antibody.
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FECH / Ferrochelatase Rabbit anti-Human Polyclonal (aa55-423) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348
FECH / Ferrochelatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
FECH / Ferrochelatase Antibody - Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FECH / Ferrochelatase Rabbit anti-Human Polyclonal (aa100-149) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$397
FECH / Ferrochelatase Antibody - Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FECH / Ferrochelatase Rabbit anti-Human Polyclonal (aa100-149) (HRP) Antibody
Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Monkey, Orangutan, Chimpanzee
WB
HRP Conjugated
100 µl/$442
FECH / Ferrochelatase Antibody - Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FECH / Ferrochelatase Rabbit anti-Human Polyclonal (aa100-149) (Biotin) Antibody
Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Monkey, Orangutan, Chimpanzee
WB
Biotin Conjugated
100 µl/$442
FECH / Ferrochelatase Antibody - Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FECH / Ferrochelatase Rabbit anti-Human Polyclonal (aa100-149) (FITC) Antibody
Zebrafish, Pig, Horse, Rabbit, Mouse, Dog, Guinea pig, Bovine, Bat, Rat, Gibbon, Human, Monkey, Orangutan, Chimpanzee
WB
FITC Conjugated
100 µl/$442
FECH / Ferrochelatase Antibody - FECH antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FECH / Ferrochelatase Rabbit anti-Human Polyclonal (aa252-301) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
FECH / Ferrochelatase Antibody - FECH antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FECH / Ferrochelatase Rabbit anti-Human Polyclonal (aa252-301) (HRP) Antibody
Human, Monkey, Chimpanzee, Orangutan, Gibbon
WB
HRP Conjugated
100 µl/$469
FECH / Ferrochelatase Antibody - FECH antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FECH / Ferrochelatase Rabbit anti-Human Polyclonal (aa252-301) (Biotin) Antibody
Human, Monkey, Chimpanzee, Orangutan, Gibbon
WB
Biotin Conjugated
100 µl/$469
FECH / Ferrochelatase Antibody - FECH antibody Western blot of MCF7 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FECH / Ferrochelatase Rabbit anti-Human Polyclonal (aa252-301) (FITC) Antibody
Human, Monkey, Chimpanzee, Orangutan, Gibbon
WB
FITC Conjugated
100 µl/$469
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FECH / Ferrochelatase Mouse anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µg/$705
FECH / Ferrochelatase Antibody - FECH antibody ARP41865_P050-NP_001012533-FECH(ferrochelatase (protoporphyria)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FECH / Ferrochelatase Rabbit anti-Human Polyclonal (aa51-100) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
FECH / Ferrochelatase Antibody - FECH antibody ARP41865_P050-NP_001012533-FECH(ferrochelatase (protoporphyria)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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FECH / Ferrochelatase Rabbit anti-Human Polyclonal (aa51-100) (HRP) Antibody
Rabbit, Human, Monkey
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
FECH / Ferrochelatase Antibody - FECH antibody ARP41865_P050-NP_001012533-FECH(ferrochelatase (protoporphyria)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
FECH / Ferrochelatase Rabbit anti-Human Polyclonal (aa51-100) (Biotin) Antibody
Rabbit, Human, Monkey
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
FECH / Ferrochelatase Antibody - FECH antibody ARP41865_P050-NP_001012533-FECH(ferrochelatase (protoporphyria)) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human liver.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
FECH / Ferrochelatase Rabbit anti-Human Polyclonal (aa51-100) (FITC) Antibody
Rabbit, Human, Monkey
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
FECH / Ferrochelatase Antibody - 1:100 staining human lymph carcinoma tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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FECH / Ferrochelatase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
FECH / Ferrochelatase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$669
FECH / Ferrochelatase Antibody - Detection limit for recombinant GST tagged FECH is 0.03 ng/ml as a capture antibody.
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FECH / Ferrochelatase Mouse anti-Human Monoclonal (3H3) Antibody
Human
ELISA
Unconjugated
100 µg/$423
FECH / Ferrochelatase Antibody - Immunohistochemistry of paraffin-embedded Human cervical cancer tissue  using FECH Polyclonal Antibody at dilution of 1:55(×200)
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FECH / Ferrochelatase Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
FECH / Ferrochelatase Antibody
Select
FECH / Ferrochelatase Rabbit anti-Human Polyclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321
Select
FECH / Ferrochelatase Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
Select
FECH / Ferrochelatase Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
Viewing 1-25 of 46 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).