FDPS

farnesyl diphosphate synthase

FDPS is an enzyme that catalyzes the production of geranyl pyrophosphate and farnesyl pyrophosphate from isopentenyl pyrophosphate and dimethylallyl pyrophosphate. The resulting product, farnesyl pyrophosphate, is a key intermediate in cholesterol and sterol biosynthesis, a substrate for protein farnesylation and geranylgeranylation, and a ligand or agonist for certain hormone receptors and growth receptors. Drugs that inhibit this enzyme prevent the post-translational modifications of small GTPases and have been used to treat diseases related to bone resorption. Multiple pseudogenes have been found on chromosomes 1, 7, 14, 15, 21 and X. Multiple transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (10)

Type

Over-Expression Lysate (4)

Recombinant (6)

Target

FDPS (10)

Publications

No (10)

Tag

6His-SUMO, N-terminus (1)

GST (1)

GST, N-terminus (1)

His,N-terminus (1)

His-GST (2)

Myc-DDK (Flag) (4)

Species

Human (7)

Rat (1)

Source

293T Cells (2)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (3)

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Human FDPS Protein (Recombinant 6His-SUMO, N-terminus) (aa1-419) - LS-G56260

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human FDPS Protein (Recombinant GST, N-terminus) (aa320-419) - LS-G58548

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human FDPS Protein (Recombinant His-GST) (aa1-419) - LS-G25425

Source:

E. coli

Tag:

His-GST

Molecular Weight:

78.3 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Rat FDPS Protein (Recombinant His-GST) (aa1-353) - LS-G25426

Source:

E. coli

Tag:

His-GST

Molecular Weight:

70.8 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human FDPS Protein (Recombinant GST) (Full Length) - LS-G28455

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

74.7 kDa

Price:

10 µg/$479; 25 µg/$670

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FDPS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G125558

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.1 kDa

Price:

100 µg/$494

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Human FDPS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75885

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.1 kDa

Price:

20 µg/$150

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Human FDPS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75886

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.1 kDa

Price:

20 µg/$150

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FDPS Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99615

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48.1 kDa

Price:

100 µg/$494

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Human FDPS Protein (Recombinant His,N-terminus) (Met1-Lys353) - LS-G140725

Source:

E. coli

Tag:

His,N-terminus

Molecular Weight:

42.4 kDa

Price:

50 µg/$721

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