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FDFT1 / Squalene Synthase

farnesyl-diphosphate farnesyltransferase 1

FDFT1 / Squalene Synthase encodes a membrane-associated enzyme located at a branch point in the mevalonate pathway. The encoded protein is the first specific enzyme in cholesterol biosynthesis, catalyzing the dimerization of two molecules of farnesyl diphosphate in a two-step reaction to form squalene.

Gene Name: farnesyl-diphosphate farnesyltransferase 1
Synonyms: FDFT1, DGPT, ERG9, SS, Squalene synthetase, SQS, FPP:FPP farnesyltransferase, Squalene synthase
Target Sequences: NM_004462 NP_004453.3 P37268

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Proteins (9)
Over-Expression Lysate (2)
Recombinant (7)
FDFT1 / Squalene Synthase (9)
No (9)
6His, N-terminus (1)
GST (1)
His (4)
Myc-DDK (Flag) (3)
Human (6)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (5)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (3)
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293T Cells
Myc-DDK (Flag)
47.9 kDa
20 µg/$150
FDFT1 / Squalene Synthase Protein - Recombinant Farnesyl Diphosphate Farnesyltransferase 1 By SDS-PAGE
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E. coli
His
18.5 kDa
10 µg/$279; 50 µg/$425; 100 µg/$680; 200 µg/$850; 1 mg/$1,944; 500 µg/$1,490; 5 mg/$2,969; 2 mg/$2,131
FDFT1 / Squalene Synthase Protein - Recombinant Farnesyl Diphosphate Farnesyltransferase 1 By SDS-PAGE
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E. coli
His
27.9 kDa
10 µg/$286; 50 µg/$472; 100 µg/$752; 200 µg/$942; 1 mg/$2,069; 500 µg/$1,600; 5 mg/$3,291; 2 mg/$2,257
FDFT1 / Squalene Synthase Protein - Recombinant Farnesyl Diphosphate Farnesyltransferase 1 By SDS-PAGE
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E. coli
His
24.7 kDa
10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225
FDFT1 / Squalene Synthase Protein
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E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
FDFT1 / Squalene Synthase Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
1 mg/$1,355; 100 µg/$420; 20 µg/$323
FDFT1 / Squalene Synthase Protein - Purified recombinant protein FDFT1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
47.9 kDa
20 µg/$1,107
FDFT1 / Squalene Synthase Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
47.9 kDa
100 µg/$494
FDFT1 / Squalene Synthase Protein - 12.5% SDS-PAGE of human FDFT1 stained with Coomassie Blue
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Wheat Germ Extract
GST
71.61 kDa
10 µg/$479; 25 µg/$670
Viewing 1-9 of 9 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).