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FCGR3A / CD16A

Fc fragment of IgG, low affinity IIIa, receptor (CD16a)

FCGR3A / CD16A is a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
Synonyms: FCGR3A, CD16A, CD16a antigen, CD16, FcgammaRIIIA, FCR-10, FCRIII, Fc gamma receptor III-A, Fc-gamma RIII, Fc-gamma RIII-alpha, FCG3, IGFR3, Fc- gamma riii, Fc-gamma receptor IIIb (CD16), Fc-gamma RIIIa, FCGR3, FCRIIIA, Neutrophil-specific antigen NA, Igg fc receptor iii-1, IgG Fc receptor III-2, Igg fc receptors iii-1, FCGRIII
Target Sequences: NM_000569 NP_000560.5 P08637

Publications (1)

1
In Vitro Exposure to Prostratin but Not Bryostatin-1 Improves Natural Killer Cell Functions Including Killing of CD4+ T Cells Harboring Reactivated Human Immunodeficiency Virus. Desimio MG, Giuliani E, Ferraro AS, Adorno G, Doria M. Frontiers in immunology. 2018 June;9: [Full Text Article] [PubMed:30008723] [PMC:PMC6033996]

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ELISA Kits (10)
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FCGR3A / CD16A (10)
Human (6)
Guinea pig (1)
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12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (8)
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Plasma (6)
Serum (6)
Tissue Homogenates (3)
FCGR3A / CD16A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
FCGR3A / CD16A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$798
FCGR3A / CD16A ELISA Kit
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Sandwich
96-Well Microplate
Human
7.813 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
FCGR3A / CD16A ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
1.563 - 100 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
FCGR3A / CD16A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
7.813 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
FCGR3A / CD16A ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
7.813 - 500 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FCGR3A / CD16A ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
0.391 - 25 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FCGR3A / CD16A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
7.813 - 500 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FCGR3A / CD16A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FCGR3A / CD16A ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
47 - 3000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$897
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).