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FBXO30 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it is upregulated in nasopharyngeal carcinoma.
Gene Name: | F-box protein 30 |
Family/Subfamily: | F-Box |
Synonyms: | FBXO30, F-box protein 30, F-box domain protein, F-box only protein 30, FBX30 |
Target Sequences: | NM_032145 NP_115521.3 Q8TB52 |
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