FBP1

fructose-1,6-bisphosphatase 1

Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.

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Products

Proteins (14)

Type

Over-Expression Lysate (4)

Recombinant (10)

Target

FBP1 (14)

Publications

No (14)

Tag

10His-SUMO, N-terminus + Myc, C-terminus (1)

6His, C-terminus (4)

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (6)

Species

Human (12)

Source

293T Cells (2)

E. coli (5)

HEK 293 Cells (4)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (1)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (4)

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Human FBP1 Protein (Recombinant GST) (Full Length) - LS-G28446

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

62.92 kDa

Price:

10 µg/$479; 25 µg/$670

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Human FBP1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65657

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.7 kDa

Price:

20 µg/$1,107

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Human FBP1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65658

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.7 kDa

Price:

20 µg/$1,107

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Human FBP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75985

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.7 kDa

Price:

20 µg/$150

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Human FBP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75986

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.7 kDa

Price:

20 µg/$150

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FBP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123126

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.7 kDa

Price:

100 µg/$494

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FBP1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124676

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.7 kDa

Price:

100 µg/$494

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Human FBP1 Protein (Recombinant 6His, C-terminus) (Ala2-Gln338) - LS-G139324

Source:

E. coli

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

37.9 kDa

Price:

10 µg/$358; 50 µg/$458

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Human FBP1 Protein (Recombinant GST, N-terminus) (aa1-338) - LS-G56257

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human FBP1 Protein (Recombinant 6His, C-terminus) (Ala2-Gln338) - LS-G139325

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

37.8 kDa

Price:

10 µg/$358; 50 µg/$458

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Human FBP1 Protein (Recombinant His) - LS-G629

Source:

E. coli

Tag:

His

Price:

100 µg/$342; 500 µg/$641; 20 µg/$254

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Human FBP1 Protein (Recombinant 10His-SUMO, N-terminus + Myc, C-terminus) (aa2-338) - LS-G56252

Source:

E. coli

Tag:

10His-SUMO, N-terminus + Myc, C-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human FBP1 Protein (Recombinant 6His, C-terminus) (Ala2-Gln338) - LS-G39511

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

37.8kD

Price:

10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157

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Human FBP1 Protein (Recombinant 6His, C-terminus) (Ala2-Gln338) - LS-G38675

Source:

E. coli

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

37.89kD

Price:

10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157

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