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FBN1 / Fibrillin 1

fibrillin 1

Fibrillins are structural components of 10-12 nm extracellular calcium-binding microfibrils, which occur either in association with elastin or in elastin-free bundles. Fibrillin-1-containing microfibrils provide long-term force bearing structural support. Regulates osteoblast maturation by controlling TGF-beta bioavailability and calibrating TGF-beta and BMP levels, respectively.

Gene Name: fibrillin 1
Synonyms: FBN1, ACMICD, Fibrillin 1, Fibrillin-1, FBN, ECTOL1, GPHYSD2, MASS, MFS1, OCTD, SSKS, WMS2, Fibrillin 1 (Marfan syndrome), Fibrillin 15, SGS, WMS
Target Sequences: NM_000138 P35555

Publications (4)

1
Defining the Extracellular Matrix of Rhabdomyosarcoma. Xiaolei Lian, J Steffan Bond, Narendra Bharathy, Sergei P Boudko, Elena Pokidysheva, Jack F Shern, Melvin Lathara, Takako Sasaki, Teagan Settelmeyer, Megan M Cleary, Ayeza Bajwa, Ganapati Srinivasa, Christopher P Hartley, Hans Peter Bächinger, Atiya Mansoor, Sakir H Gultekin, Noah E Berlow, Charles Keller. Frontiers in oncology. 2021 March;11:601957. [Full Text Article] [PubMed:33708626] [PMC:PMC7942227] Related Antibodies: LS-B5512.
2
FBXO2 Promotes Proliferation of Endometrial Cancer by Ubiquitin-Mediated Degradation of FBN1 in the Regulation of the Cell Cycle and the Autophagy Pathway. Xiaoxia Che, Fangfang Jian, Ying Wang, Jingjing Zhang, Jian Shen, Qi Cheng, Xi Wang, Nan Jia, Weiwei Feng. Frontiers in cell and developmental biology. 2020 September;8:843. [Full Text Article] [PubMed:32984335] [PMC:PMC7487413] Related Antibodies: LS-B5512.
3
Impairment of chondrogenesis and microfibrillar network in Adamtsl2 deficiency. Laure Delhon, Clémentine Mahaut, Nicolas Goudin, Emilie Gaudas, Kevin Piquand, Wilfried Le Goff, Valérie Cormier-Daire, Carine Le Goff. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 2019 Feb;33:2707-2718. [Full Text Article] [PubMed:30303737] Related Antibodies: LS-C358981.
4
Aqueous humor TGFß and fibrillin-1 in Tsk mice reveal clues to POAG pathogenesis. James C Tan, MinHee K Ko, Jeong-Im Woo, Kenneth L Lu, Jonathan A Kelber. Scientific reports. 2024 February;14:3517. [Full Text Article] [PubMed:38347040]
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FBN1 / Fibrillin 1 (23)
Human (8)
Mouse (6)
Rat (2)
Chicken (1)
Monkey (2)
Pig (1)
Porcine (1)
Rabbit (1)
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12 x 8-Well Microstrips (2)
96-Well Microplate (2)
96-Well Strip Plate (18)
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Cell Culture Supernatants (2)
Cell Lysates (2)
Cell Supernatant (1)
Plasma (17)
Serum (17)
Tissue Homogenates (9)
FBN1 / Fibrillin 1 ELISA Kit
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Sandwich CLIA
96-Well Strip Plate
Human
27.4 - 20000 pg/ml
Chemiluminescent
Plasma, Serum, Tissue Homogenates
1 Plate/$851
FBN1 / Fibrillin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$764
FBN1 / Fibrillin 1 ELISA Kit
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Sandwich
96-Well Microplate
Mouse
7.813 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
FBN1 / Fibrillin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
7.813 - 500 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
FBN1 / Fibrillin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$715
FBN1 / Fibrillin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
FBN1 / Fibrillin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Supernatant, Plasma, Serum
1 Plate/$669
FBN1 / Fibrillin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
1 Plate/$782
FBN1 / Fibrillin 1 ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
500 Wells/$1,041; 1000 Wells/$1,512
FBN1 / Fibrillin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
FBN1 / Fibrillin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
FBN1 / Fibrillin 1 ELISA Kit
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Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
FBN1 / Fibrillin 1 ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$669
FBN1 / Fibrillin 1 ELISA Kit
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Sandwich
96-Well Microplate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
FBN1 / Fibrillin 1 ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Mouse
3.125 - 200 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
FBN1 / Fibrillin 1 ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
1 - 25 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
FBN1 / Fibrillin 1 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
FBN1 / Fibrillin 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
FBN1 / Fibrillin 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FBN1 / Fibrillin 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FBN1 / Fibrillin 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FBN1 / Fibrillin 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FBN1 / Fibrillin 1 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$968
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).