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FBLN5 / Fibulin 5

fibulin 5

FBLN5 / Fibulin 5 is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).

Gene Name: fibulin 5
Synonyms: FBLN5, ARCL1A, ARMD3, FIBL-5, ADCL2, EVEC, Fibulin 5, Urine p50 protein, DANCE, Fibulin-5, UP50
Target Sequences: NM_006329 NP_006320.2 Q9UBX5

Publications (3)

1
Fibulin 5, a human Wharton's jelly-derived mesenchymal stem cells-secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin-RAC1 signaling axis. So Yeon Won, Soojin Kwon, Hui Su Jeong, Ki Wha Chung, Byung-Ok Choi, Jong Wook Chang, Ji Eun Lee. Stem cells (Dayton, Ohio). 2020 October; [Full Text Article] [PubMed:33107705] [PMC:PMC7756588]
2
A Non-Invasive Determination of LOXL1 and Fibulin-5 Levels in the Vaginal Secretions of Women with and Without Pelvic Organ Prolapse. Bobby Garcia, Afiba Arthur, Bansari Patel, Jenny Chang, Dongbao Chen, Felicia Lane. Journal of medical research and surgery. 2021 Apr;;2:10.52916/jmrs214042. [Full Text Article] [PubMed:34318305] [PMC:PMC8312730]
3
TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex. Nicole Merritt , Keith Garcia , Dushyandi Rajendran, Zhen-Yuan Lin, Xiaomeng Zhang, Katrina A Mitchell, Nicholas Borcherding, Colleen Fullenkamp, Michael S Chimenti, Anne-Claude Gingras, Kieran F Harvey, Munir R Tanas. eLife. 2021 April;10:e62857. [Full Text Article] [PubMed:33913810] [PMC:PMC8143797] Related Antibodies: LS-B14518.

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ELISA Kits (17)
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FBLN5 / Fibulin 5 (17)
Human (7)
Mouse (2)
Rat (1)
Chicken (1)
Guinea pig (1)
Monkey (1)
Porcine (1)
Rabbit (1)
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12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (15)
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Cell Culture Supernatants (1)
Plasma (8)
Serum (8)
Tissue Homogenates (3)
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FBLN5 / Fibulin 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Urine
1 Plate/$730
FBLN5 / Fibulin 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
10 - 250 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
FBLN5 / Fibulin 5 ELISA Kit
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Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
FBLN5 / Fibulin 5 ELISA Kit
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Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
FBLN5 / Fibulin 5 ELISA Kit
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Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
FBLN5 / Fibulin 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
FBLN5 / Fibulin 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
FBLN5 / Fibulin 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
FBLN5 / Fibulin 5 ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
0.625 - 40 ng/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
FBLN5 / Fibulin 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FBLN5 / Fibulin 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FBLN5 / Fibulin 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FBLN5 / Fibulin 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FBLN5 / Fibulin 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
FBLN5 / Fibulin 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Sheep
1.563 - 100 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$691
FBLN5 / Fibulin 5 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates
1 Plate/$897
FBLN5 / Fibulin 5 ELISA Kit
Select
Sandwich
96-Well Microplate
Human
3.125 - 200 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).