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FBLN5 / Fibulin 5
fibulin 5
FBLN5 / Fibulin 5 is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).
| Gene Name: | fibulin 5 |
| Synonyms: | FBLN5, ARCL1A, ARMD3, FIBL-5, ADCL2, EVEC, Fibulin 5, Urine p50 protein, DANCE, Fibulin-5, UP50 |
| Target Sequences: | NM_006329 NP_006320.2 Q9UBX5 |
Publications (3)
1
Fibulin 5, a human Wharton's jelly-derived mesenchymal stem cells-secreted paracrine factor, attenuates peripheral nervous system myelination defects through the Integrin-RAC1 signaling axis. So Yeon Won, Soojin Kwon, Hui Su Jeong, Ki Wha Chung, Byung-Ok Choi, Jong Wook Chang, Ji Eun Lee. Stem cells (Dayton, Ohio). 2020 October; [Full Text Article]
[PubMed:33107705]
[PMC:PMC7756588]
2
A Non-Invasive Determination of LOXL1 and Fibulin-5 Levels in the Vaginal Secretions of Women with and Without Pelvic Organ Prolapse. Bobby Garcia, Afiba Arthur, Bansari Patel, Jenny Chang, Dongbao Chen, Felicia Lane. Journal of medical research and surgery. 2021 Apr;;2:10.52916/jmrs214042. [Full Text Article]
[PubMed:34318305]
[PMC:PMC8312730]
3
TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex. Nicole Merritt , Keith Garcia , Dushyandi Rajendran, Zhen-Yuan Lin, Xiaomeng Zhang, Katrina A Mitchell, Nicholas Borcherding, Colleen Fullenkamp, Michael S Chimenti, Anne-Claude Gingras, Kieran F Harvey, Munir R Tanas. eLife. 2021 April;10:e62857. [Full Text Article]
[PubMed:33913810]
[PMC:PMC8143797]
Related Antibodies: LS-B14518.
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FBLN5 / Fibulin 5 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Urine
1 Plate/$730
FBLN5 / Fibulin 5 Rabbit anti-Human Polyclonal (140-220 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
FBLN5 / Fibulin 5 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$351
FBLN5 / Fibulin 5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
FBLN5 / Fibulin 5 Rabbit anti-Human Polyclonal (aa99-205) (Biotin) Antibody
Human
ICC, WB
Biotin Conjugated
100 µl/$319
FBLN5 / Fibulin 5 Rabbit anti-Human Polyclonal (aa171-220) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
FBLN5 / Fibulin 5 Goat anti-Human Polyclonal (aa505-518) Antibody
Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
FBLN5 / Fibulin 5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$331
Wheat Germ Extract
GST
76.6 kDa
10 µg/$479; 25 µg/$670
Sandwich
96-Well Strip Plate
Human
10 - 250 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
E. coli
His
15.5 kDa
10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209
FBLN5 / Fibulin 5 Mouse anti-Human Monoclonal (3F10A5, 3F8A12) Antibody
Human
ELISA, IHC, WB
Unconjugated
0.1 ml/$419
FBLN5 / Fibulin 5 Mouse anti-Human Monoclonal (1G6A4) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$467
FBLN5 / Fibulin 5 Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
FBLN5 / Fibulin 5 Mouse anti-Human Monoclonal (Amino Acid: 242-448) (1G6A4) Antibody
Human
IHC, WB
Unconjugated
100 µl/$518
FBLN5 / Fibulin 5 Mouse anti-Human Monoclonal (3F10A5, 3F8A12) Antibody
Human
IHC, WB
Unconjugated
100 µl/$541
FBLN5 / Fibulin 5 Mouse anti-Human Monoclonal (3F8D5) Antibody
Human
ELISA, WB
Unconjugated
0.1 ml/$393
FBLN5 / Fibulin 5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
0.1 mg/$379
FBLN5 / Fibulin 5 Rabbit anti-Human Polyclonal (aa393-421) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
FBLN5 / Fibulin 5 Rabbit anti-Human Polyclonal (aa393-421) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
FBLN5 / Fibulin 5 Rabbit anti-Human Polyclonal (aa393-421) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
FBLN5 / Fibulin 5 Rabbit anti-Human Polyclonal (aa393-421) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
FBLN5 / Fibulin 5 Rabbit anti-Human Polyclonal (aa393-421) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
FBLN5 / Fibulin 5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
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