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FBG4 / FBXO17 is a member of the F-box protein family which is characterized by the F-box motif. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it contains an F-box domain. Alternative splicing results in multiple transcript variants.
Gene Name: | F-box protein 17 |
Family/Subfamily: | F-Box |
Synonyms: | FBXO17, F-box only protein 26, F-box only protein 17, FBG4, Fbx17, FBX26, FBXO26, F-box protein 17, F-box protein FBG4 |
Target Sequences: | NM_024907 NP_079183.4 Q96EF6 |
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