FAT10 / UBD

ubiquitin D

Ubiquitin-like protein modifier which can be covalently attached to target protein and subsequently leads to their degradation by the 26S proteasome, in a NUB1L-dependent manner. Probably functions as a survival factor. Conjugation ability activated by UBA6. Promotes the expression of the proteasome subunit beta type-9 (PSMB9/LMP2). Regulates TNF-alpha-induced and LPS-mediated activation of the central mediator of innate immunity NF-kappa-B by promoting TNF-alpha-mediated proteasomal degradation of ubiquitinated-I-kappa-B-alpha. Required for TNF-alpha-induced p65 nuclear translocation in renal tubular epithelial cells (RTECs). May be involved in dendritic cell (DC) maturation, the process by which immature dendritic cells differentiate into fully competent antigen-presenting cells that initiate T-cell responses. Mediates mitotic non-disjunction and chromosome instability, in long-term in vitro culture and cancers, by abbreviating mitotic phase and impairing the kinetochore localization of MAD2L1 during the prometaphase stage of the cell cycle. May be involved in the formation of aggresomes when proteasome is saturated or impaired. Mediates apoptosis in a caspase-dependent manner, especially in renal epithelium and tubular cells during renal diseases such as polycystic kidney disease and Human immunodeficiency virus (HIV)-associated nephropathy (HIVAN).

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Products

ELISA Kits (12)

Type

Custom (2)

Sandwich (9)

Sandwich CLIA (1)

Target

FAT10 / UBD (12)

Reactivity

Human (5)

Mouse (1)

Rat (1)

Chicken (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Format

12 x 8-Well Microstrips (1)

96-Well Microplate (1)

96-Well Strip Plate (10)

Publications

No (12)

Sample Type

Cell Culture Supernatants (1)

Plasma (5)

Serum (5)

Tissue Homogenates (2)

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Mouse FAT10 / UBD (Sandwich ELISA) ELISA Kit - LS-F18419

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$669

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Human FAT10 / UBD (Sandwich ELISA) ELISA Kit - LS-F4934

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

3.13 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$798

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Human FAT10 / UBD (Custom ELISA) ELISA Kit - LS-F18420

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Rat FAT10 / UBD (Custom ELISA) ELISA Kit - LS-F18421

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Human FAT10 / UBD (CLIA) ELISA Kit - LS-F29807

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

0.781 - 50 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Human FAT10 / UBD (Sandwich ELISA) ELISA Kit - LS-F35074

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rabbit FAT10 / UBD (Sandwich ELISA) ELISA Kit - LS-F48942

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

125 - 8000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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Chicken FAT10 / UBD (Sandwich ELISA) ELISA Kit - LS-F48941

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Porcine FAT10 / UBD (Sandwich ELISA) ELISA Kit - LS-F48943

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Sheep FAT10 / UBD (Sandwich ELISA) ELISA Kit - LS-F48944

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$691

Select

Monkey FAT10 / UBD (Sandwich ELISA) ELISA Kit - LS-F48939

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Human FAT10 / UBD (Sandwich ELISA) ELISA Kit - LS-F21809

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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