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Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.
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FASLG / Fas Ligand
Fas ligand (TNF superfamily, member 6)
Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.
Human circulating CD4+CD25highFoxp3+ regulatory T cells kill autologous CD8+ but not CD4+ responder cells by Fas-mediated apoptosis. Strauss L, Bergmann C, Whiteside TL. Journal of immunology (Baltimore, Md. : 1950). 2009 182:1469-80.
[PubMed:19155494]
Related Antibodies: LS-C40984.
2
Lipopolysaccharide can trigger a cathepsin B-dependent programmed death response in human endothelial cells. Li JH, D'Alessio A, Pober JS. The American journal of pathology. 2009 175:1124-35.
[PubMed:19661440]
[PMC:PMC2731131]
Related Antibodies: LS-C40984.
3
Intensive resistance exercise induces lymphocyte apoptosis via cortisol and glucocorticoid receptor-dependent pathways. Krger K, Agnischock S, Lechtermann A, Tiwari S, Mishra M, Pilat C, Wagner A, Tweddell C, Gramlich I, Mooren FC. Journal of applied physiology (Bethesda, Md. : 1985). 2011 110:1226-32.
[PubMed:21393471]
Related Antibodies: LS-C40984.
4
Efficient Nef-mediated downmodulation of TCR-CD3 and CD28 is associated with high CD4+ T cell counts in viremic HIV-2 infection. Khalid M, Yu H, Sauter D, Usmani SM, Schmokel J, Feldman J, Gruters RA, van der Ende ME, Geyer M, Rowland-Jones S, Osterhaus AD, Kirchhoff F. Journal of virology. 2012 86:4906-20.
[PubMed:22345473]
[PMC:PMC3347365]
Related Antibodies: LS-C40984.
5
Phenotypic and functional characterization of human T-cell subsets in response to influenza A viruses. Qin G, Liu Y, Zheng J, Xiang Z, Ng IH, Malik Peiris JS, Lau YL, Tu W. The Journal of infectious diseases. 2012 205:1646-53.
[PubMed:22457284]
Related Antibodies: LS-C40984.
6
CD8+ T cells use TRAIL to restrict West Nile virus pathogenesis by controlling infection in neurons. Shrestha B, Pinto AK, Green S, Bosch I, Diamond MS. Journal of virology. 2012 86:8937-48.
[PubMed:22740407]
[PMC:PMC3416144]
Related Antibodies: LS-C40984.
7
Exercise delays neutrophil apoptosis by a G-CSF-dependent mechanism. Mooren FC, Vlker K, Klocke R, Nikol S, Waltenberger J, Krger K. Journal of applied physiology (Bethesda, Md. : 1985). 2012 113:1082-90.
[PubMed:22858628]
Related Antibodies: LS-C40984.
8
IL-1ß Promotes a New Function of DNase I as a Transcription Factor for the Fas Receptor Gene. Thiyagarajan D, Pedersen HL, Seredkina N, Horvei KD, Arranz L, Sonneveld R, Nijenhuis T, van der Vlag J, Rekvig OP. Frontiers in cell and developmental biology. 2018 February;6:7. (Human)[Full Text Article]
[PubMed:29468159]
[PMC:PMC5807897]
Related Antibodies: LS-C176019.
9
Pre-treatment With Ranibizumab Aggravates PDT Injury and Alleviates Inflammatory Response in Choroid-Retinal Endothelial Cells. Yang Liu, Min Zhu, Ruowen Gong, Xin Wang, Lei Li, Gezhi Xu. Frontiers in cell and developmental biology. 2020 August;8:608. [Full Text Article]
[PubMed:32733897]
[PMC:PMC7363772]
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PLEASE NOTE
For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.
The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).