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FARSB encodes a highly conserved enzyme that belongs to the aminoacyl-tRNA synthetase class IIc subfamily. This enzyme comprises the regulatory beta subunits that form a tetramer with two catalytic alpha subunits. In the presence of ATP, this tetramer is responsible for attaching L-phenylalanine to the terminal adenosine of the appropriate tRNA. A pseudogene located on chromosome 10 has been identified.
Gene Name: | phenylalanyl-tRNA synthetase, beta subunit |
Synonyms: | FARSB, FARSLB, FRSB, HSPC173, PheHB, PheRS |
Target Sequences: | NM_005687 NP_005678.3 Q9NSD9 |
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