FANCA

Fanconi anemia, complementation group A

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group A. Alternative splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are the most common cause of Fanconi anemia.

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Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

FANCA (5)

Publications

No (5)

Tag

GST (1)

His (1)

His, N-Terminal (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

Baculovirus (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

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Human FANCA Protein (Recombinant GST) (Full Length) - LS-G28428

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

58.41 kDa

Price:

10 µg/$479; 25 µg/$670

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Human FANCA Protein (Recombinant His) (Met1-Cys297) - LS-G97453

Source:

Baculovirus

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

35.2 kDa

Price:

100 µg/$843

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Human FANCA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84124

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.8 kDa

Price:

20 µg/$150

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Human FANCA Protein (Recombinant His, N-Terminal) - LS-G145148

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

32.8 kDa

Price:

50 µg/$419

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FANCA Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121195

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.8 kDa

Price:

100 µg/$494

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