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Required for MAP kinase p38 (MAPK11, MAPK12, MAPK13 and/or MAPK14) activation during gastrulation. Required for down-regulation of E-cadherin during gastrulation by regulating E-cadherin protein level downstream from NCK-interacting kinase (NIK) and independently of the regulation of transcription by FGF signaling and Snail By similarity. Required for starvation-induced ATG9A trafficking during autophagy.
Gene Name: | suppressor of Ty 20 homolog (S. cerevisiae) |
Synonyms: | SUPT20H, BA421P11.4, C13orf19, FP757, p38-interacting protein, Protein FAM48A, SPT20, Tumor rejection antigen, p38IP, C13, FAM48A, p38 interacting protein |
Target Sequences: | NM_017569 NP_060039.1 Q8NEM7 |
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