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FA2H / FAAH

fatty acid 2-hydroxylase

FA2H / FAAH is a protein that catalyzes the synthesis of 2-hydroxysphingolipids, a subset of sphingolipids that contain 2-hydroxy fatty acids. Sphingolipids play roles in many cellular processes and their structural diversity arises from modification of the hydrophobic ceramide moiety, such as by 2-hydroxylation of the N-acyl chain, and the existence of many different head groups. Mutations in this gene have been associated with leukodystrophy dysmyelinating with spastic paraparesis with or without dystonia.

Gene Name: fatty acid 2-hydroxylase
Synonyms: FA2H, Fatty acid alpha-hydroxylase, FAXDC1, Fatty acid 2-hydroxylase, SCS7, FAH1, SPG35
Target Sequences: NM_024306 NP_077282.3 Q7L5A8

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Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
FA2H / FAAH (4)
No (4)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
FA2H / FAAH Protein - Purified recombinant protein FA2H was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
42.6 kDa
20 µg/$1,107
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293T Cells
Myc-DDK (Flag)
42.6 kDa
20 µg/$150
FA2H / FAAH Protein - 12.5% SDS-PAGE of human FA2H stained with Coomassie Blue
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Wheat Germ Extract
GST
69.2 kDa
10 µg/$479; 25 µg/$670
FA2H / FAAH Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
42.6 kDa
100 µg/$494
Viewing 1-4 of 4 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).