F12 / Factor XII

coagulation factor XII (Hageman factor)

F12 / Factor XII is coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged.

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Products

ELISA Kits (32)

Type

Competitive EIA (1)

Custom (3)

Sandwich (24)

Sandwich CLIA (4)

Target

F12 / Factor XII (32)

Reactivity

Human (9)

Mouse (7)

Rat (5)

Chicken (2)

Guinea pig (1)

Monkey (2)

Pig (1)

Porcine (1)

Rabbit (2)

Sheep (1)

Format

12 x 8-Well Microstrips (5)

96-Well Microplate (4)

96-Well Strip Plate (23)

Publications

No (31)

Yes (1)

Sample Type

Plasma (23)

Serum (18)

Tissue Homogenates (4)

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Mouse F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F21335

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Mouse F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F10441

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.1 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$823

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Human F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F10418

(4.1) Rating

(2) Publication(s)

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.5 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$499

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Human F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F4434

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$764

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Rat F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F15049

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.78 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F13176

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

78 - 5000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Sheep F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F42458

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

23.438 - 1500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$691

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Pig F12 / Factor XII (Custom ELISA) ELISA Kit - LS-F15050

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Pig

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Bovine F12 / Factor XII (Custom ELISA) ELISA Kit - LS-F15051

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Mouse F12 / Factor XII (Custom ELISA) ELISA Kit - LS-F15052

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Mouse F12 / Factor XII (CLIA) ELISA Kit - LS-F30595

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Mouse F12 / Factor XII (Competitive EIA) ELISA Kit - LS-F28336

Type:

Competitive EIA

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.5 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Human F12 / Factor XII (CLIA) ELISA Kit - LS-F29565

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

15.625 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Human F12 / Factor XII (CLIA) ELISA Kit - LS-F30100

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

15.625 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Rat F12 / Factor XII (CLIA) ELISA Kit - LS-F31186

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Rat

Range:

125 - 8000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Human F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F23732

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

46.875 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$528

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Rat F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F22633

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.63 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F26872

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

5 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Human F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F32825

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Monkey F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F38512

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

1.563 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Mouse F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F36862

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

3.125 - 200 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Rat F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F36865

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Porcine F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F38552

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Porcine

Range:

46.875 - 3000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Rat F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F74287

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma

Price:

1 Plate/$834

Select

Rabbit F12 / Factor XII (Sandwich ELISA) ELISA Kit - LS-F47512

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rabbit

Range:

0.469 - 30 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

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