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F11 / FXI / Factor XI

coagulation factor XI

F11 / FXI / Factor XI is coagulation factor XI of the blood coagulation cascade. This protein is present in plasma as a zymogen, which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds. During activation of the plasma factor XI, an internal peptide bond is cleaved by factor XIIa (or XII) in each of the two chains, resulting in activated factor XIa, a serine protease composed of two heavy and two light chains held together by disulfide bonds. This activated plasma factor XI triggers the middle phase of the intrisic pathway of blood coagulation by activating factor IX. Defects in this factor lead to Rosenthal syndrome, a blood coagulation abnormality.

Gene Name: coagulation factor XI
Family/Subfamily: Protease , Serine S1
Synonyms: F11, Coagulation factor XI, Factor xi deficiency, F11 deficiency, Factor XI, PTA deficiency, PTA, Rosenthal syndrome, FXI
Target Sequences: NM_000128 NP_000119.1 P03951

☰ Filters
Products
Proteins (10)
Over-Expression Lysate (2)
Recombinant (8)
F11 / FXI / Factor XI (10)
No (10)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
His,C-terminus (1)
His-GST (1)
His-T7 (2)
Myc-DDK (Flag) (3)
Human (7)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (4)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (3)
Low endotoxin level (1)
F11 / FXI / Factor XI Protein
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E. coli
His-T7
30.0 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
F11 / FXI / Factor XI Protein - Recombinant Coagulation Factor XI By SDS-PAGE
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E. coli
His-GST
59.6 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
F11 / FXI / Factor XI Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
F11 / FXI / Factor XI Protein - Purified recombinant protein F11 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
69.9 kDa
20 µg/$1,107
F11 / FXI / Factor XI Protein - Recombinant Coagulation Factor XI By SDS-PAGE
Select
E. coli
His-T7
28.9 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
F11 / FXI / Factor XI Protein - 12.5% SDS-PAGE of human F11 stained with Coomassie Blue
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Wheat Germ Extract
GST
96.5 kDa
2 µg/$439
F11 / FXI / Factor XI Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
69.9 kDa
100 µg/$710
F11 / FXI / Factor XI Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
69.9 kDa
20 µg/$215
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
69.5 kDa
50 µg/$1,070
F11 / FXI / Factor XI Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).