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F10 / Factor X

coagulation factor X

F10 / Factor X is the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity.

Gene Name: coagulation factor X
Family/Subfamily: Protease , Serine S1
Synonyms: F10, Factor X, FX, Factor X deficiency, Stuart factor, Stuart-Prower factor, Coagulation factor X, Factor Xa, FXA, Prothrombinase
Target Sequences: NM_000504 NP_000495.1 P00742

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Products
Antibodies (77)
Primary (77)
F10 / Factor X (77)
Human (55)
Mouse (37)
Rat (13)
Bovine (1)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Guinea pig (3)
Monkey (3)
Pig (4)
Rabbit (1)
Sheep (1)
IHC (8)
IHC-P (5)
WB (56)
Flo (1)
ELISA (47)
ICC (1)
ID (2)
IE (4)
IF (3)
Peptide-ELISA (3)
RIA (1)
rabbit (37)
mouse (15)
goat (3)
rat (4)
sheep (18)
Product Group
IHCPlus (2)
IgG (42)
IgG1 (11)
IgG1,k (2)
monoclonal mc (20)
polyclonal pc (57)
058 (1)
10 (1)
3C8-B9 (1)
4E3-F8 (1)
5050/8.H.4 (1)
5051 (1)
9050 (1)
9051 (1)
CaFX-50 (2)
OTI1B8 (2)
OTI1D12 (2)
OTI3A9 (2)
APC (1)
APC Conjugated (1)
Biotin Conjugated (6)
Carrier-free (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (6)
HRP Conjugated (6)
PE Conjugated (1)
Preservative Free (2)
Unconjugated (55)
aa21-481 (8)
aa41-488 (6)
aa351-400 (4)
190-270 aa, Internal (1)
370-450 aa, N-terminal (1)
Internal (1)
aa216-265 (1)
aa22-71 (1)
aa314-485 (1)
aa33-312 (1)
aa351-381 (1)
activated heavy chain, Cleaved-Ile235 (1)
light chain,Cleaved-Ala41 (1)
No (77)
F10 / Factor X Antibody - Anti-F10 / Factor X antibody IHC staining of human vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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F10 / Factor X Sheep anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
F10 / Factor X Antibody - Anti-F10 / Factor X antibody IHC of human small intestine, vessels. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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F10 / Factor X Sheep anti-Human Polyclonal Antibody
Human
ELISA, ID, IE, IHC, IHC-P
Unconjugated
50 µg/$575
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F10 / Factor X Mouse anti-Human Monoclonal (5050/8.H.4) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$444
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F10 / Factor X Goat anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IE
HRP Conjugated
200 µg/$611
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F10 / Factor X Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IE
HRP Conjugated
200 µg/$657
F10 / Factor X Antibody - Western blot of extracts from A549 cells, treated with etoposide 24 uM 24h, using FA10 (light chain, Cleaved-Ala41) Antibody. The lane on the right is treated with the synthesized peptide.
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F10 / Factor X Rabbit anti-Human Polyclonal (aa22-71) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
F10 / Factor X Antibody - 721_B cell lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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F10 / Factor X Rabbit anti-Human Polyclonal (aa351-400) Antibody
Human
WB
Unconjugated
100 µl/$424
F10 / Factor X Antibody - Immunofluorescence analysis of A549 cells using F10 antibody. Blue: DAPI for nuclear staining.
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F10 / Factor X Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, WB
Unconjugated
20 µl/$275; 100 µl/$389
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F10 / Factor X Mouse anti-Bovine Monoclonal (5051) Antibody
Rabbit, Dog, Sheep, Bovine, Pig, Human
ELISA, RIA, WB
Unconjugated
100 µg/$444
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F10 / Factor X Sheep anti-Mouse Polyclonal (FITC) Antibody
Mouse
ELISA
FITC Conjugated
100 µg/$479; 1 mg/$689
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F10 / Factor X Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
500 µg/$657
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F10 / Factor X Goat anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
1 mg/$439; 10 mg/$725
F10 / Factor X Antibody - F10 Antibody IHC of formalin-fixed and paraffin-embedded human hepatocarcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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F10 / Factor X Rabbit anti-Human Polyclonal (aa351-381) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
400 µl/$393
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F10 / Factor X Rat anti-Mouse Monoclonal Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$533
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F10 / Factor X Rat anti-Mouse Monoclonal (9050) Antibody
Mouse, Human
ELISA, WB
Unconjugated
100 µg/$428; 500 µg/$763
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F10 / Factor X Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P
Unconjugated
100 µl/$412
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F10 / Factor X Mouse anti-Human Monoclonal (3C8-B9) Antibody
Human
ELISA, WB
Unconjugated
1 mg/$1,801; 100 µg/$4,756
F10 / Factor X Antibody - Western blot of extracts of HepG2 cell lines, using F10 antibody.
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F10 / Factor X Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
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F10 / Factor X Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$427; 1 ml/$572
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F10 / Factor X Rabbit anti-Human Monoclonal (Preservative Free) (058) Antibody
Human
ELISA
Unconjugated, Preservative Free
20 µl/$271; 100 µl/$412
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F10 / Factor X Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
100 µg/$482; 1 mg/$695; 10 mg/$3,757
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F10 / Factor X Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
100 µg/$482; 1 mg/$695
F10 / Factor X Antibody - IHC of paraffin-embedded A549 xenograft using Factor X antibody at 1:500 dilution.
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F10 / Factor X Rabbit anti-Human Polyclonal (aa33-312) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
F10 / Factor X Antibody - 1:100 staining mouse liver tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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F10 / Factor X Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
F10 / Factor X Antibody
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F10 / Factor X Rabbit anti-Human Polyclonal (aa314-485) Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µl/$332
Viewing 1-25 of 77 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).