EXOSC10

exosome component 10

Putative catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the nucleus, the RNA exosome complex is involved in proper maturation of stable RNA species such as rRNA, snRNA and snoRNA, in the elimination of RNA processing by-products and non-coding 'pervasive' transcripts, such as antisense RNA species and promoter-upstream transcripts (PROMPTs), and of mRNAs with processing defects, thereby limiting or excluding their export to the cytoplasm. The RNA exosome may be involved in Ig class switch recombination (CSR) and/or Ig variable region somatic hypermutation (SHM) by targeting AICDA deamination activity to transcribed dsDNA substrates. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA. EXOSC10 has 3'-5' exonuclease activity By similarity. EXOSC10 is required for nucleolar localization of C1D and probably mediates the association of SKIV2L2, C1D and MPP6 wth the RNA exosome involved in the maturation of 5.8S rRNA.

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Products

Antibodies (20)

Proteins (3)

Type

Over-Expression Lysate (2)

Primary (20)

Recombinant (1)

Target

EXOSC10 (23)

Reactivity

Human (20)

Mouse (8)

Rat (1)

Bat (3)

Bovine (6)

Chimpanzee (3)

Dog (6)

Gibbon (6)

Rabbit (6)

Application

IHC (13)

IHC-P (10)

WB (14)

ELISA (4)

IF (2)

IP (3)

Peptide-ELISA (1)

Host

rabbit (19)

mouse (1)

Product Group

IHCPlus (1)

Isotype

IgG (15)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (19)

Clone

1E6 (1)

Format

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

Unconjugated (11)

Epitope

C-Terminus (4)

aa756-805 (4)

aa200-250 (1)

aa750-800 (1)

aa835-885 (1)

Publications

No (23)

Tag

GST (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

Select

EXOSC10 Antibody (C-Terminus) LS-C31532

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$397

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EXOSC10 Antibody (C-Terminus, HRP) LS-C439922

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal (C-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Bat, Gibbon, Human, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$442

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EXOSC10 Antibody (C-Terminus, Biotin) LS-C439920

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal (C-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Bat, Gibbon, Human, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

EXOSC10 Antibody (C-Terminus, FITC) LS-C439919

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal (C-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Bat, Gibbon, Human, Chimpanzee

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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EXOSC10 Antibody LS-C665447

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

EXOSC10 Antibody (aa756-805) LS-B12591

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal (aa756-805) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$375

Select

EXOSC10 Antibody (aa756-805, HRP) LS-C439923

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal (aa756-805) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Human, Gibbon

Applications:

IHC, IHC-P, WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

EXOSC10 Antibody (aa756-805, Biotin) LS-C439921

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal (aa756-805) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Human, Gibbon

Applications:

IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

EXOSC10 Antibody (aa756-805, FITC) LS-C439924

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal (aa756-805) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Dog, Bovine, Human, Gibbon

Applications:

IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

EXOSC10 Antibody LS-C665446

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC

Format:

Unconjugated

Price:

100 µg/$351

Select

EXOSC10 Antibody LS-C669758

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

Select

EXOSC10 Antibody (HRP) LS-C674945

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

EXOSC10 Antibody (Biotin) LS-C669760

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

EXOSC10 Antibody (FITC) LS-C669759

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

EXOSC10 Antibody (aa750-800) LS-C290634

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal (aa750-800) Antibody

Reactivity:

Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

EXOSC10 Antibody (aa200-250) LS-C290633

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal (aa200-250) Antibody

Reactivity:

Mouse, Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

EXOSC10 Antibody (clone 1E6) LS-C197933

Antibody:

EXOSC10 Mouse anti-Human Monoclonal (1E6) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$335

Select

EXOSC10 Antibody LS-C803368

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$282; 200 µl/$350

Select

EXOSC10 Antibody (aa835-885) LS-C290635

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal (aa835-885) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

EXOSC10 Antibody LS-C816329

Antibody:

EXOSC10 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P

Format:

Unconjugated

Price:

100 µl/$302

Select

Human EXOSC10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74676

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

100.7 kDa

Price:

20 µg/$150

Select

Human EXOSC10 Protein (Recombinant GST) (Full Length) - LS-G29788

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

127.2 kDa

Price:

10 µg/$479; 25 µg/$670

Select

EXOSC10 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122783

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

100.7 kDa

Price:

100 µg/$494

Viewing 1-23 of 23 product results

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