EXOC2 / SEC5

exocyst complex component 2

EXOC2 / SEC5 is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants.

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Proteins (2)

Type

Over-Expression Lysate (2)

Target

EXOC2 / SEC5 (2)

Publications

No (2)

Tag

Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

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EXOC2 / SEC5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111826

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

103.9 kDa

Price:

100 µg/$494

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Human EXOC2 / SEC5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G90918

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

103.9 kDa

Price:

20 µg/$150

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