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EXOC1 / SEC3 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described.
Gene Name: | exocyst complex component 1 |
Synonyms: | EXOC1, BM-102, Exocyst complex component 1, SEC3-like 1 (S. cerevisiae), SEC3L1, SEC3P, SEC3-like 1, Exocyst complex component Sec3, SEC3 |
Target Sequences: | NM_018261 NP_060731.2 Q9NV70 |
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