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Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA. Component of the transient SURF complex which recruits UPF1 to stalled ribosomes in the context of nonsense-mediated decay (NMD) of mRNAs containing premature stop codons.
Gene Name: | eukaryotic translation termination factor 1 |
Synonyms: | ETF1, D5S1995, ERF1, Eukaryotic release factor 1, Protein Cl1, RF1, SUP45L1, TB3-1 |
Target Sequences: | NM_004730 NP_004721.1 P62495 |
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