ESET / SETDB1

SET domain, bifurcated 1

Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3. H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. H3 'Lys-9' trimethylation is coordinated with DNA methylation. Probably forms a complex with MBD1 and ATF7IP that represses transcription and couples DNA methylation and histone 'Lys-9' trimethylation. Its activity is dependent on MBD1 and is heritably maintained through DNA replication by being recruited by CAF-1. SETDB1 is targeted to histone H3 by TRIM28/TIF1B, a factor recruited by KRAB zinc-finger proteins.

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Products

Antibodies (27)

Type

Primary (27)

Target

ESET / SETDB1 (27)

Reactivity

Human (27)

Mouse (10)

Rat (6)

Chimpanzee (3)

Monkey (2)

Non-Human Primate (2)

Orangutan (3)

Application

IHC (8)

IHC-P (2)

WB (26)

ELISA (14)

ICC (1)

IF (3)

Peptide-ELISA (1)

Host

rabbit (21)

mouse (6)

Product Group

IHCPlus (1)

Isotype

IgG (14)

IgG1 (6)

Clonality

monoclonal mc (6)

polyclonal pc (21)

Clone

5H6A12 (2)

5H6D4 (2)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (2)

PE Conjugated (1)

Unconjugated (19)

Epitope

aa1193-1225 (7)

N-Terminus (4)

aa1-397 (1)

aa1125-1175 (1)

Publications

No (26)

Yes (1)

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IHC-plus™ ESET / SETDB1 Antibody LS-B720

(5.0) Rating

(4) Publication(s)

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$515

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ESET / SETDB1 Antibody (clone 5H6A12) LS-C169282

Antibody:

ESET / SETDB1 Mouse anti-Human Monoclonal (5H6A12) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, WB

Format:

Unconjugated

Price:

100 µl/$435

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ESET / SETDB1 Antibody (clone 5H6A12) LS-C758892

Antibody:

ESET / SETDB1 Mouse anti-Human Monoclonal (5H6A12) Antibody

Reactivity:

Mouse, Human, Non-Human Primate

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$541

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ESET / SETDB1 Antibody LS-C482531

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$266; 50 µl/$286; 100 µl/$321; 200 µl/$386

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ESET / SETDB1 Antibody (aa1-397) LS-C377483

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal (aa1-397) Antibody

Reactivity:

Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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ESET / SETDB1 Antibody LS-C812592

Antibody:

ESET / SETDB1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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ESET / SETDB1 Antibody LS-C751841

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

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ESET / SETDB1 Antibody LS-C770562

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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ESET / SETDB1 Antibody LS-C341945

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$356; 100 µl/$461

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ESET / SETDB1 Antibody LS-C832291

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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ESET / SETDB1 Antibody (clone 5H6D4) LS-C169281

Antibody:

ESET / SETDB1 Mouse anti-Human Monoclonal (5H6D4) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$424

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ESET / SETDB1 Antibody LS-C334524

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$287; 100 µl/$431

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ESET / SETDB1 Antibody LS-C812590

Antibody:

ESET / SETDB1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Mouse, Human, Monkey

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$332; 100 µg/$404; 200 µg/$505

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ESET / SETDB1 Antibody (aa1193-1225) LS-C328637

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal (aa1193-1225) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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ESET / SETDB1 Antibody (aa1193-1225, Biotin) LS-C282645

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal (aa1193-1225) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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ESET / SETDB1 Antibody (aa1193-1225, FITC) LS-C282648

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal (aa1193-1225) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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ESET / SETDB1 Antibody (aa1193-1225, Azide-free, HRP) LS-C282650

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal (aa1193-1225) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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ESET / SETDB1 Antibody (aa1193-1225, PE) LS-C282651

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal (aa1193-1225) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

ESET / SETDB1 Antibody (aa1193-1225, APC) LS-C282646

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal (aa1193-1225) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• HRP, Azide-free
• PE
• APC

• Unconjugated
• Biotin
• FITC
• More...
  • HRP, Azide-free
  • PE
  • APC

Select

ESET / SETDB1 Antibody LS-C803575

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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ESET / SETDB1 Antibody (clone 5H6D4) LS-C758643

Antibody:

ESET / SETDB1 Mouse anti-Human Monoclonal (5H6D4) Antibody

Reactivity:

Mouse, Human, Non-Human Primate

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$518

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ESET / SETDB1 Antibody (aa1125-1175) LS-C287050

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal (aa1125-1175) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µg/$295; 100 µl/$514

Select

ESET / SETDB1 Antibody (N-Terminus) LS-C201353

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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ESET / SETDB1 Antibody (N-Terminus, Biotin) LS-C437897

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Human, Chimpanzee, Orangutan

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

• Unconjugated
• Biotin

• Unconjugated
• Biotin

Select

ESET / SETDB1 Antibody (aa1193-1225) LS-C96614

Antibody:

ESET / SETDB1 Rabbit anti-Human Polyclonal (aa1193-1225) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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