Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
Transcriptional activator that may play a role in regulating epithelial cell differentiation and proliferation. May act as a repressor for a specific subset of ETS/AP-1-responsive genes and as a modulator of the nuclear response to mitogen-activated protein kinase signaling cascades. Binds to DNA sequences containing the consensus nucleotide core sequence GGAA. Involved in regulation of TNFRSF10B/DR5 expression through Ets-binding sequences on the TNFRSF10B/DR5 promoter. May contribute to development and carcinogenesis by acting as a tumor suppressor gene or anti-oncogene.
Gene Name: | ets homologous factor |
Synonyms: | EHF, ESE3, ESE3B, ESE-3, ESE3 transcription factor, Ets homologous factor, ESEJ, HEHF |
Target Sequences: | NM_012153 NP_036285.2 Q9NZC4 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.