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ERLEC1 is a resident endoplasmic reticulum (ER) protein that functions in N-glycan recognition. This protein is thought to be involved in ER-associated degradation via its interaction with the membrane-associated ubiquitin ligase complex. It also functions as a regulator of multiple cellular stress-response pathways in a manner that promotes metastatic cell survival. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 21.
Gene Name: | endoplasmic reticulum lectin 1 |
Synonyms: | ERLEC1, C20orf30, CL24936, CL25084, CIM, Erlectin 1, Erlectin, XTP3TPB, XTP3-transactivated protein B, C2orf30, Endoplasmic reticulum lectin 1, ER lectin, XTP3-B |
Target Sequences: | NM_015701 BAA91974.1 Q96DZ1 |
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