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ERGIC-53 / LMAN1

lectin, mannose-binding, 1

ERGIC-53 / LMAN1 is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.

Gene Name: lectin, mannose-binding, 1
Synonyms: LMAN1, ERGIC53, F5F8D, gp58, ERGIC-53, FMFD1, Lectin mannose-binding 1, MCFD1, MR60, Protein ERGIC-53, Lectin, mannose-binding, 1
Target Sequences: NM_005570 NP_005561.1 P49257

☰ Filters
Antibodies (37)
ELISA Kits (4)
Proteins (4)
Custom (2)
Over-Expression Lysate (2)
Primary (37)
Recombinant (2)
Sandwich (2)
ERGIC-53 / LMAN1 (45)
Human (39)
Mouse (10)
Rat (13)
Bat (6)
Bovine (3)
Chicken (3)
Chimpanzee (3)
Dog (12)
Gibbon (6)
Horse (3)
Monkey (11)
Pig (3)
Rabbit (3)
Zebrafish (3)
IHC (9)
IHC-P (8)
WB (33)
Flo (6)
ELISA (3)
ICC (1)
IF (7)
IP (2)
Peptide-ELISA (1)
rabbit (27)
mouse (10)
Product Group
IHCPlus (2)
IgG (18)
IgG1 (10)
monoclonal mc (10)
polyclonal pc (27)
1B8 (2)
2B10 (2)
OTI1A8 (2)
OTI1C5 (2)
OTI1E3 (2)
96-Well Strip Plate (4)
APC (1)
APC Conjugated (1)
Biotin Conjugated (4)
Carrier-free (5)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (1)
Unconjugated (21)
aa198-475 (8)
aa301-350 (4)
aa36-85 (4)
aa150-200 (1)
No (45)
Plasma (2)
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His-T7 (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
ERGIC-53 / LMAN1 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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ERGIC-53 / LMAN1 Mouse anti-Human Monoclonal (2B10) Antibody
Human, Monkey
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$485
ERGIC-53 / LMAN1 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-LMAN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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ERGIC-53 / LMAN1 Mouse anti-Human Monoclonal (OTI1C5) Antibody
Human, Monkey
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
ERGIC-53 / LMAN1 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-LMAN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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ERGIC-53 / LMAN1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1C5) Antibody
Human, Monkey
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ERGIC-53 / LMAN1 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-LMAN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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ERGIC-53 / LMAN1 Mouse anti-Human Monoclonal (OTI1A8) Antibody
Dog, Rat, Human, Monkey
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$450
ERGIC-53 / LMAN1 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-LMAN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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ERGIC-53 / LMAN1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1A8) Antibody
Dog, Rat, Human, Monkey
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ERGIC-53 / LMAN1 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:50.
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ERGIC-53 / LMAN1 Mouse anti-Human Monoclonal (1B8) Antibody
Dog, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
50 µl/$460
ERGIC-53 / LMAN1 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-LMAN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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ERGIC-53 / LMAN1 Mouse anti-Human Monoclonal (OTI1E3) Antibody
Dog, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
ERGIC-53 / LMAN1 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-LMAN1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
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ERGIC-53 / LMAN1 Mouse anti-Human Monoclonal (Carrier-free) (OTI1E3) Antibody
Dog, Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
ERGIC-53 / LMAN1 Antibody - Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ERGIC-53 / LMAN1 Rabbit anti-Human Polyclonal (aa36-85) Antibody
Human
WB
Unconjugated
100 µl/$424
ERGIC-53 / LMAN1 Antibody - Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ERGIC-53 / LMAN1 Rabbit anti-Human Polyclonal (aa36-85) (HRP) Antibody
Chicken, Bovine, Rat, Pig, Horse, Bat, Mouse, Dog, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
ERGIC-53 / LMAN1 Antibody - Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ERGIC-53 / LMAN1 Rabbit anti-Human Polyclonal (aa36-85) (Biotin) Antibody
Chicken, Bovine, Rat, Pig, Horse, Bat, Mouse, Dog, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
ERGIC-53 / LMAN1 Antibody - Fetal heart lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
ERGIC-53 / LMAN1 Rabbit anti-Human Polyclonal (aa36-85) (FITC) Antibody
Chicken, Bovine, Rat, Pig, Horse, Bat, Mouse, Dog, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
ERGIC-53 / LMAN1 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
ERGIC-53 / LMAN1 Mouse anti-Human Monoclonal (Carrier-free) (2B10) Antibody
Human, Monkey
IF, WB
Unconjugated, Carrier-free
100 µg/$511
ERGIC-53 / LMAN1 Antibody - IHC analysis of LMAN1 using anti-LMAN1 antibody. LMAN1 was detected in paraffin-embedded section of human appendicitis tissue. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti-LMAN1 Antibody overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC) with DAB as the chromogen.
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ERGIC-53 / LMAN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
ERGIC-53 / LMAN1 Antibody - IHC staining of FFPE human glioma with LMAN1 antibody at 1ug/ml. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 10-20 min followed by cooling at RT for 20 min.
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ERGIC-53 / LMAN1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC-P, WB
Unconjugated
100 µg/$575
ERGIC-53 / LMAN1 Antibody - Immunohistochemistry image at a dilution of 1:300 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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ERGIC-53 / LMAN1 Rabbit anti-Human Polyclonal Antibody
Human
IF, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
Select
ERGIC-53 / LMAN1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$341
ERGIC-53 / LMAN1 Antibody - Western blot of ERGIC-53 / LMAN1 antibody.
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ERGIC-53 / LMAN1 Rabbit anti-Human Polyclonal (aa198-475) Antibody
Human
ICC, IP, WB
Unconjugated
100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225
ERGIC-53 / LMAN1 Antibody - Western blot of ERGIC-53 / LMAN1 antibody.
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ERGIC-53 / LMAN1 Rabbit anti-Human Polyclonal (aa198-475) (APC) Antibody
Human
WB
APC Conjugated
100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451
ERGIC-53 / LMAN1 Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE), at a dilution of 1:50.
Select
ERGIC-53 / LMAN1 Mouse anti-Human Monoclonal (Carrier-free) (1B8) Antibody
Dog, Rat, Human, Monkey
WB
Unconjugated, Carrier-free
100 µg/$511
ERGIC-53 / LMAN1 Antibody - Western blot analysis of LMAN1 using mouse brain lysates
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ERGIC-53 / LMAN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
ERGIC-53 / LMAN1 Antibody - Lane A: Marker. Lane B: HepG2 cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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ERGIC-53 / LMAN1 Rabbit anti-Human Polyclonal (aa301-350) Antibody
Human
WB
Unconjugated
100 µl/$397
ERGIC-53 / LMAN1 Antibody - Western blot analysis of extracts of various cell lines, using LMAN1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 5s.
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ERGIC-53 / LMAN1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
ERGIC-53 / LMAN1 Antibody
Select
ERGIC-53 / LMAN1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
Select
ERGIC-53 / LMAN1 Rabbit anti-Human Polyclonal (aa150-200) Antibody
Human
IP
Unconjugated
10 µg/$295; 100 µl/$514
Viewing 1-25 of 45 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).