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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Preferentially hydrolyzes the basic residues Arg and Lys.
Gene Name: | endoplasmic reticulum aminopeptidase 2 |
Family/Subfamily: | Exopeptidase , Metallopeptidase M1 |
Synonyms: | ERAP2, Aminopeptidase, L-RAP, LRAP |
Target Sequences: | NM_022350 NP_071745.1 Q6P179 |
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