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EPHX2 / Epoxide Hydrolase 2

epoxide hydrolase 2, cytoplasmic

Soluble Epoxide Hydrolase (sEH) also known as cytosolic Epoxide Hydrolase is a phase I xenobiotic-metabolizing enzyme that converts epoxyeicosatrienoic acids (EETs) into their corresponding dihydroxyeicosatrienoic acids (DHETs). EETs are thought to be involved in vascular tone, ion channel regulation, mitogenesis and cell signaling. DHETs have, in general, less biological activity then EETs and are more readily excreted, thus hydration of EETs by sEH maybe a means of attenuating or eliminating their activity. sEHs have been identified in many tissues including liver, kidney, adrenal, pancreatic islets, gi tract and vascular smooth muscle.

Gene Name: epoxide hydrolase 2, cytoplasmic
Synonyms: EPHX2, CEH, Epoxide hydratase, Epoxide hydrolase, soluble, Epoxide hydrolase 2, cytosolic, SEH, Soluble epoxide hydrolase
Target Sequences: NM_001979 NP_001970.2 P34913

Publications (1)

1
Activity of sEH and Oxidant Status during Systemic Bovine Coliform Mastitis. Vengai Mavangira, Matthew J Kuhn, Angel Abuelo, Christophe Morisseau, Bruce D Hammock, Lorraine M Sordillo. Antioxidants (Basel, Switzerland). 2021 May;10: [Full Text Article] [PubMed:34065244] [PMC:PMC8161397] Related Antibodies: LS-B6940.

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Antibodies (37)
Primary (37)
EPHX2 / Epoxide Hydrolase 2 (37)
Human (36)
Mouse (6)
Rat (7)
Bovine (1)
Horse (1)
Monkey (2)
Pig (1)
Rabbit (1)
IHC (19)
IHC-P (11)
WB (33)
Flo (6)
ELISA (7)
IF (9)
IP (1)
Peptide-ELISA (3)
rabbit (24)
mouse (11)
goat (2)
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IHCPlus (4)
Ig (1)
IgG (18)
IgG1 (10)
monoclonal mc (10)
polyclonal pc (27)
OTI1A6 (2)
OTI1H5 (2)
OTI2F2 (2)
OTI2G2 (2)
OTI3F6 (2)
APC Conjugated (1)
Biotin Conjugated (2)
Carrier-free (5)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (29)
aa1-555 (4)
N-Terminus (2)
C-Terminus (1)
Internal (1)
No (36)
Yes (1)
EPHX2 / Epoxide Hydrolase 2 Antibody - Anti-EPHX2 antibody IHC of human brain, cortex neurons. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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EPHX2 / Epoxide Hydrolase 2 Rabbit anti-Human Polyclonal Antibody
Rabbit, Bovine, Pig, Horse, Human
IHC, IHC-P, WB
Unconjugated
500 µl/$485
EPHX2 / Epoxide Hydrolase 2 Antibody - Anti-EPHX2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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EPHX2 / Epoxide Hydrolase 2 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
EPHX2 / Epoxide Hydrolase 2 Antibody - Immunohistochemical analysis of EPHX2 staining in rat kidney formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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EPHX2 / Epoxide Hydrolase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$286; 100 µl/$321; 200 µl/$386
EPHX2 / Epoxide Hydrolase 2 Antibody - Immunohistochemistry of paraffin-embedded rat kidney tissue.
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EPHX2 / Epoxide Hydrolase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
EPHX2 / Epoxide Hydrolase 2 Antibody - Anti-EPHX2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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EPHX2 / Epoxide Hydrolase 2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
EPHX2 / Epoxide Hydrolase 2 Antibody - Anti-EPHX2 antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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EPHX2 / Epoxide Hydrolase 2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
EPHX2 / Epoxide Hydrolase 2 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-EPHX2 mouse monoclonal antibody.
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EPHX2 / Epoxide Hydrolase 2 Mouse anti-Human Monoclonal (OTI1A6) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
EPHX2 / Epoxide Hydrolase 2 Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-EPHX2 mouse monoclonal antibody.
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EPHX2 / Epoxide Hydrolase 2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1A6) Antibody
Human
IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
EPHX2 / Epoxide Hydrolase 2 Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EPHX2 / Epoxide Hydrolase 2 Rabbit anti-Human Polyclonal (aa1-555) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
EPHX2 / Epoxide Hydrolase 2 Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EPHX2 / Epoxide Hydrolase 2 Rabbit anti-Human Polyclonal (aa1-555) (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
EPHX2 / Epoxide Hydrolase 2 Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EPHX2 / Epoxide Hydrolase 2 Rabbit anti-Human Polyclonal (aa1-555) (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
EPHX2 / Epoxide Hydrolase 2 Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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EPHX2 / Epoxide Hydrolase 2 Rabbit anti-Human Polyclonal (aa1-555) (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
EPHX2 / Epoxide Hydrolase 2 Antibody - Western blot analysis of Jurkat cell lysates using EPXH2 antibody. The lane on the left is treated with the antigen-specific peptide.
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EPHX2 / Epoxide Hydrolase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
EPHX2 / Epoxide Hydrolase 2 Antibody - Anti-EPHX2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY EPHX2.
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EPHX2 / Epoxide Hydrolase 2 Mouse anti-Human Monoclonal (OTI2F2) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
EPHX2 / Epoxide Hydrolase 2 Antibody - Anti-EPHX2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY EPHX2.
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EPHX2 / Epoxide Hydrolase 2 Mouse anti-Human Monoclonal (Carrier-free) (OTI2F2) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
EPHX2 / Epoxide Hydrolase 2 Antibody - Anti-EPHX2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY EPHX2.
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EPHX2 / Epoxide Hydrolase 2 Mouse anti-Human Monoclonal (OTI2G2) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
EPHX2 / Epoxide Hydrolase 2 Antibody - Anti-EPHX2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY EPHX2.
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EPHX2 / Epoxide Hydrolase 2 Mouse anti-Human Monoclonal (Carrier-free) (OTI2G2) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
EPHX2 / Epoxide Hydrolase 2 Antibody - Anti-EPHX2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY EPHX2.
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EPHX2 / Epoxide Hydrolase 2 Mouse anti-Human Monoclonal (OTI3F6) Antibody
Human
Flo, IF, WB
Unconjugated
100 µl/$434
EPHX2 / Epoxide Hydrolase 2 Antibody - Anti-EPHX2 mouse monoclonal antibody  immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY EPHX2.
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EPHX2 / Epoxide Hydrolase 2 Mouse anti-Human Monoclonal (Carrier-free) (OTI3F6) Antibody
Human
Flo, IF, WB
Unconjugated, Carrier-free
100 µg/$511
EPHX2 / Epoxide Hydrolase 2 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-EPHX2 mouse monoclonal antibody.
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EPHX2 / Epoxide Hydrolase 2 Mouse anti-Human Monoclonal (OTI1H5) Antibody
IHC, IHC-P, WB
Unconjugated
100 µl/$434
EPHX2 / Epoxide Hydrolase 2 Antibody - Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-EPHX2 mouse monoclonal antibody.
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EPHX2 / Epoxide Hydrolase 2 Mouse anti-Human Monoclonal (Carrier-free) (OTI1H5) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
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EPHX2 / Epoxide Hydrolase 2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
100 µg/$351
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EPHX2 / Epoxide Hydrolase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$356; 100 µl/$461
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EPHX2 / Epoxide Hydrolase 2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
EPHX2 / Epoxide Hydrolase 2 Antibody - All lanes: Anti-EPHX2 Antibody (N-Term) at 1:2000 dilution Lane 1: Jurkat whole cell lysate Lane 2: human fetal kidney lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 63 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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EPHX2 / Epoxide Hydrolase 2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$393
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).