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Catalyzes the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in extracellular proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). Specifically glycosylates the Thr residue located between the fifth and sixth conserved cysteines of folded EGF-like domains.
Gene Name: | EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase |
Synonyms: | EOGT, AER61, C3orf64, EOGT1, AER61 glycosyltransferase |
Target Sequences: | Q5NDL2 Q5NDL2 |
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