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EN2

engrailed homeobox 2

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system.

Gene Name: engrailed homeobox 2
Synonyms: EN2, AUTS10, Engrailed homolog 2, Engrailed homeobox 2, Homeobox protein engrailed-2, Engrailed-2, Homeobox protein en-2, Hu-En-2
Target Sequences: NM_001427 NP_001418.2 P19622

Publications (1)

1
Engrailed-2 (EN2) - a novel biomarker in epithelial ovarian cancer. McGrath SE, Annels N, Madhuri TK, Tailor A, Butler-Manuel SA, Morgan R, Pandha H, Michael A. BMC cancer. 2018 October;18:943. [Full Text Article] [PubMed:30285763] [PMC:PMC6171236] Related Antibodies: LS-B3477.

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
EN2 (5)
No (5)
GST, N-terminus (1)
His, N-Terminal (1)
Myc-DDK (Flag) (3)
Human (4)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
EN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
34 kDa
20 µg/$150
EN2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
34 kDa
100 µg/$494
EN2 Protein - Recombinant Engrailed Homeobox Protein 2 (EN2) by SDS-PAGE
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E. coli
His, N-Terminal
23.7kDa
10 µg/$271; 50 µg/$382; 200 µg/$762; 100 µg/$610; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$3,041
EN2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
EN2 Protein - Purified recombinant protein EN2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
34 kDa
20 µg/$1,107
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).