ELF4 / MEF

E74-like factor 4 (ets domain transcription factor)

Transcriptional activator that binds to DNA sequences containing the consensus 5'-WGGA-3'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity). Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 (By similarity). Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway.

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Products

Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

ELF4 / MEF (6)

Publications

No (6)

Tag

GST, N-terminus (1)

GST, N-terminus + His, C-terminus (1)

Myc-DDK (Flag) (4)

Species

Human (4)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

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Human ELF4 / MEF Protein (Recombinant GST, N-terminus) (aa521-612) - LS-G58441

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human ELF4 / MEF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81520

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.5 kDa

Price:

20 µg/$150

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Human ELF4 / MEF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81522

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.5 kDa

Price:

20 µg/$150

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Human ELF4 / MEF Protein (Recombinant GST, N-terminus + His, C-terminus) - LS-G145214

Source:

E. coli

Tag:

GST, N-terminus + His, C-terminus

Molecular Weight:

98.5 kDa

Price:

50 µg/$419

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ELF4 / MEF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99434

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.5 kDa

Price:

100 µg/$494

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ELF4 / MEF Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124558

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

70.5 kDa

Price:

100 µg/$494

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