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Interacts with RB1 and EP300 and acts as a repressor of MYOD1 transactivation. Inhibits EP300 and CBP histone acetyltransferase activity. May be involved in coupling cell cycle exit to the transcriptional activation of genes required for cellular differentiation. May act as a candidate coinhibitory factor for NR0B2 that can be directly linked to transcription inhibitory mechanisms.
Gene Name: | EP300 interacting inhibitor of differentiation 1 |
Synonyms: | EID1, 21 kDa pRb-associated protein, C15orf3, CREBBP/EP300 inhibitor 1, EID-1, PNAS-22, IRO45620, PTD014, RBP21, CRI1, NB4 apoptosis related protein |
Target Sequences: | NM_014335 NP_055150.1 Q9Y6B2 |
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