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EGR3 is a transcriptional regulator that belongs to the EGR family of C2H2-type zinc-finger proteins. It is an immediate-early growth response gene which is induced by mitogenic stimulation. The protein encoded by this gene participates in the transcriptional regulation of genes in controling biological rhythm. It may also play a role in a wide variety of processes including muscle development, lymphocyte development, endothelial cell growth and migration, and neuronal development. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
Gene Name: | early growth response 3 |
Synonyms: | EGR3, Early growth response 3, EGR-3, PILOT, Zinc finger protein pilot |
Target Sequences: | NM_004430 NP_004421.2 Q06889 |
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