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EFCAB6 is a protein which directly binds the oncogene DJ-1 and androgen receptor to form a ternary complex in cells. This binding protein recruits histone-deacetylase complexes in order to repress transcription activity of androgen receptor. This protein may also play a role in spermatogenesis and fertilization. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene Name: | EF-hand calcium binding domain 6 |
Synonyms: | EFCAB6, DJ-1-binding protein, DJBP, HSCBCIP1, KIAA1672, DJ185D5.1, FLJ23588 |
Target Sequences: | NM_022785 NP_073622.2 Q5THR3 |
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