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This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. With PARP1 and TXK, forms a complex that acts as a T helper 1 (Th1) cell-specific transcription factor and binds the promoter of IFN-gamma to directly regulate its transcription, and is thus involved importantly in Th1 cytokine production.
Gene Name: | eukaryotic translation elongation factor 1 alpha 1 |
Synonyms: | EEF1A1, Cervical cancer suppressor 3, CCS-3, CCS3, EEF-1, Elongation factor Tu, EEF1A, EF-Tu, EF1A, Elongation factor 1-alpha 1, GRAF-1EF, LENG7, PTI1, CTCL tumor antigen, EE1A1, EEF1A-1, EF-1-alpha-1, EF1a-like protein, HNGC:16303 |
Target Sequences: | NM_001402 NP_001393.1 P68104 |
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