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EDNRB / Endothelin B Receptor

endothelin receptor type B

The Endothelin Receptor ETB is expressed in most tissues. Mutations of the receptor gene are responsible for Hirschsprung disease type 2, a multigenic disorder with phenotypes such as bicolored irides, megacolon, hypopigmentation, and hearing loss. The ETB receptor has similar affinity for all three endothelins and activates a phosphatidylinositol-calcium second messenger system. A splice variant, termed SVR, has been described; the sequence of the ETB-SVR receptor is identical to ET-B receptor, with the exception of the intracellular C-terminal domain. While both splice variants bind endothelin ET1, they exhibit different responses, which suggests that they may be functionally distinct.

Gene Name: endothelin receptor type B
Family/Subfamily: GPCR , Endothelin
Synonyms: EDNRB, ABCDS, Endothelin B receptor, Etb receptor, ET-B, Et-b receptor, Et-b-r, ET-RB, ETBR, ETRB, Etb-svr, WS4A, Endothelin receptor type B, ET-BR, ETB, HSCR, HSCR2
Target Sequences: NM_000115 NP_000106.1 P24530

☰ Filters
Products
ELISA Kits (16)
Custom (5)
Sandwich (10)
Sandwich CLIA (1)
EDNRB / Endothelin B Receptor (16)
Human (5)
Mouse (1)
Rat (3)
Chicken (1)
Dog (1)
Monkey (1)
Pig (1)
Porcine (1)
Rabbit (1)
Product Group
Alzheimer's Disease (16)
12 x 8-Well Microstrips (1)
96-Well Strip Plate (15)
No (16)
Cell Lysates (1)
Plasma (6)
Serum (6)
Tissue Homogenates (3)
EDNRB / Endothelin B Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
EDNRB / Endothelin B Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$798
EDNRB / Endothelin B Receptor ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
EDNRB / Endothelin B Receptor ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$669
EDNRB / Endothelin B Receptor ELISA Kit
Select
Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$783
EDNRB / Endothelin B Receptor ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$669
EDNRB / Endothelin B Receptor ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$669
EDNRB / Endothelin B Receptor ELISA Kit
Select
Sandwich CLIA
12 x 8-Well Microstrips
Human
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
EDNRB / Endothelin B Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
EDNRB / Endothelin B Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
EDNRB / Endothelin B Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
EDNRB / Endothelin B Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
EDNRB / Endothelin B Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
EDNRB / Endothelin B Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
78.125 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
EDNRB / Endothelin B Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
EDNRB / Endothelin B Receptor ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.5 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$805
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).