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EDN1 / Endothelin 1 is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
Gene Name: | endothelin 1 |
Family/Subfamily: | Hormone , not assigned-Hormone |
Synonyms: | EDN1, Endothelin 1, Endothelin-1, ET1, Preproendothelin-1, PPET1, HDLCQ7 |
Target Sequences: | NM_001955 NP_001946.3 P05305 |
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