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ECI1 / DCI is a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described.
Gene Name: | enoyl-CoA delta isomerase 1 |
Synonyms: | ECI1, 3,2 trans-enoyl-CoA isomerase, 3,2-trans-enoyl-CoA isomerase, Acetylene-allene isomerase, DCI, Dodecenoyl-CoA isomerase, Enoyl-CoA delta isomerase 1, D3,D2-enoyl-CoA isomerase |
Target Sequences: | NM_001919 NP_001910.2 |
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