EBI3 / IL-27B

Epstein-Barr virus induced 3

Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.

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Products

Proteins (7)

Type

Over-Expression Lysate (2)

Recombinant (5)

Target

EBI3 / IL-27B (7)

Publications

No (7)

Tag

GST (1)

GST, N-terminus (1)

GST, N-terminus + His, C-terminus (1)

His (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (5)

Mouse (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human EBI3 / IL-27B Protein (Recombinant His) (aa21-229) - LS-G15231

Source:

E. coli

Tag:

His

Molecular Weight:

24.8 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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Human EBI3 / IL-27B Protein (Recombinant GST) (Full Length) - LS-G31982

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

50.71 kDa

Price:

2 µg/$439

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Human EBI3 / IL-27B Protein (Recombinant GST, N-terminus) (aa129-229) - LS-G61392

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Mouse EBI3 / IL-27B Protein (Recombinant His-T7) (aa19-228) - LS-G25236

Source:

E. coli

Tag:

His-T7

Molecular Weight:

27.1 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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Human EBI3 / IL-27B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81119

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.4 kDa

Price:

20 µg/$150

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EBI3 / IL-27B Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115758

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.4 kDa

Price:

100 µg/$494

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Human EBI3 / IL-27B Protein (Recombinant GST, N-terminus + His, C-terminus) - LS-G145063

Source:

E. coli

Tag:

GST, N-terminus + His, C-terminus

Molecular Weight:

51.3 kDa

Price:

50 µg/$419

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