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EBAG9 / RCAS1 was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor, which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10.
Gene Name: | estrogen receptor binding site associated, antigen, 9 |
Synonyms: | EBAG9, EB9, PDAF, RCAS1 |
Target Sequences: | NM_004215 NP_004206.1 O00559 |
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