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E-FABP / FABP5 is the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.
Gene Name: | fatty acid binding protein 5 (psoriasis-associated) |
Synonyms: | FABP5, KFABP, Fatty acid-binding protein 5, PA-FABP, E-FABP, EFABP, PAFABP |
Target Sequences: | NM_001444 NP_001435.1 Q01469 |
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