Dynactin 2 / Dynamitin

dynactin 2 (p50)

Dynactin 2 / Dynamitin is a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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Products

Proteins (9)

Type

Over-Expression Lysate (2)

Recombinant (7)

Target

Dynactin 2 / Dynamitin (9)

Publications

No (9)

Tag

GST (1)

GST, N-terminus (1)

His (3)

His, N-Terminal (1)

Myc-DDK (Flag) (3)

Species

Human (8)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (4)

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Human Dynactin 2 / Dynamitin Protein (Recombinant GST) (Full Length) - LS-G32210

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

70.6 kDa

Price:

10 µg/$479; 25 µg/$670

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Human Dynactin 2 / Dynamitin Protein (Recombinant GST, N-terminus) (aa302-401) - LS-G61554

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human Dynactin 2 / Dynamitin Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65479

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.6 kDa

Price:

20 µg/$1,107

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Dynactin 2 / Dynamitin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100804

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.6 kDa

Price:

100 µg/$494

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Human Dynactin 2 / Dynamitin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75649

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.6 kDa

Price:

20 µg/$150

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Human Dynactin 2 / Dynamitin Protein (Recombinant His) - LS-G2654

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Human Dynactin 2 / Dynamitin Protein (Recombinant His) - LS-G2714

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human Dynactin 2 / Dynamitin Protein (Recombinant His) - LS-G2668

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human Dynactin 2 / Dynamitin Protein (Recombinant His, N-Terminal) (Ala2-Lys401) - LS-G133113

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

47.8kDa

Price:

10 µg/$241; 50 µg/$287; 200 µg/$382; 100 µg/$332; 1 mg/$1,111; 500 µg/$762; 5 mg/$1,921; 2 mg/$1,249

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