Orders Processing,
Shipping & Receiving,
Warehouse
2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
Production Lab
Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
DUSP9 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus.
Gene Name: | dual specificity phosphatase 9 |
Family/Subfamily: | Protein Phosphatase , Dual specificity MKP |
Synonyms: | DUSP9, Dual specificity phosphatase 9, MAP kinase phosphatase 4, MKP-4, MKP4, DUSP 9 |
Target Sequences: | NM_001395 NP_001386.1 Q99956 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.