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Most of dual-specificity protein phosphatases (DSPs) play an important role in the regulation of mitogenic signal transduction and controlling the cell cycle in response to extracellular stimuli. DUSP23 has been shown to dephosphorylate p44ERK1 but not p38 and p54SAPKbeta in vitro. Reverse transcription-PCR (RT-PCR) revealed that the DUSP23 was expressed in most fetal tissues and two adult tissues: testis and colon.
Gene Name: | dual specificity phosphatase 23 |
Family/Subfamily: | Protein Phosphatase , CDC14 |
Synonyms: | DUSP23, DUSP25, LDP3, LDP-3, RP11-190A12.1, MOSP, VH1-like phosphatase Z, VHZ, VH1-like member Z |
Target Sequences: | NM_017823 NP_060293.2 Q9BVJ7 |
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